Hyperbaric Oxygen Therapy

The first in the state of Michigan.

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Hyperbaric Oxygen Therapy (HBOT)

Hyperbaric oxygen therapy is the practice of systemically delivering greater amounts of oxygen to a patient. A pet is put in a treatment chamber and breathe close to 100% oxygen while experiencing elevated ambient pressures. This can accomplish close to miraculous results for some pets who face otherwise difficult, expensive, or seemingly hopeless medical issues.

Slide Physiological Basis of Therapy and Mechanisms of Action H.O.T. uses various action mechanisms; some related to elevated pressures and other related to how the increase in oxygen effects the body's blood stream, tissues and cells.

Atmospheric pressure greater than sea level causes increased partial pressure of oxygen, which facilitates an increase in the amount of oxygen dissolved in plasma. This causes a variety of powerful consequences:
  • Up regulation of anti-inflammatory gene expression and the down regulation of proinflammatory genetic expression, resulting in an important synergistic therapeutic method for reduction of inflammation in pathologic disease mechanisms occurring throughout the body.
  • Vasoconstriction and for the reduction of edema in the area of trauma for crush injuries. Oxygen tension levels may be 10 to 20 times that achieved by normobaric oxygen breathing.
  • Rapid dissociation of carbon monoxide molecules from hemoglobin and cytochrome A3 oxidase and delivery of physically dissolved oxygen via the plasma.
  • Increase in oxygen diffusion distance from functioning capillaries in the hypoperfused wound. Stimulation of growth and occurrence of fibroblasts, osteoclasts and granulocytes, resulting in wound healing. The resulting angiogenesis enhances healing skin grafts, select problem wounds and compromised flaps.
  • Cessation of alpha toxin production by the clostridial organisms in gas gangrene.

Slide Physiological Basis of Therapy and Mechanisms of Action H.O.T. uses various action mechanisms; some related to elevated pressures and other related to how the increase in oxygen effects the body's blood stream, tissues and cells.

Atmospheric pressure greater than sea level causes increased partial pressure of oxygen, which facilitates an increase in the amount of oxygen dissolved in plasma. This causes a variety of powerful consequences:
  • Up regulation of anti-inflammatory gene expression and the down regulation of proinflammatory genetic expression, resulting in an important synergistic therapeutic method for reduction of inflammation in pathologic disease mechanisms occurring throughout the body.
  • Vasoconstriction and for the reduction of edema in the area of trauma for crush injuries. Oxygen tension levels may be 10 to 20 times that achieved by normobaric oxygen breathing.
  • Rapid dissociation of carbon monoxide molecules from hemoglobin and cytochrome A3 oxidase and delivery of physically dissolved oxygen via the plasma.
  • Increase in oxygen diffusion distance from functioning capillaries in the hypoperfused wound. Stimulation of growth and occurrence of fibroblasts, osteoclasts and granulocytes, resulting in wound healing. The resulting angiogenesis enhances healing skin grafts, select problem wounds and compromised flaps.
  • Cessation of alpha toxin production by the clostridial organisms in gas gangrene.

Slide How it Works H.O.T. significantly increases the amount of oxygen delivered to the patient's body tissue. Benefits result from an oxygen-enriched bloodstream, and not direct contact with wounds. This is why wound dressings are left in place during treatment. Multiple of the following effects are usually experienced:
  • Enhanced wound healing
  • Increased oxygen delivery to injured tissue
  • Improved infection control
  • Greater blood vessel formation
  • Preservation of damaged tissues
  • Elimination and reduced effects of toxic substances
  • Reduction or elimination of gas-bubble obstructions
Veterinary Health
  • Fungal disease (Fungal Pneumonia)
  • Thermal burns, carbon monoxide, smoke inhalation
  • Closed head injuries
  • Ileus
  • CNS edema / Increased intracranial pressure
  • Peripheral neuropathies
  • Sports injuries (Exertional rhabdomyolysis)
  • Cellulitis, compartment syndrome
  • Ischemic injuries
  • Serious and chronic infections
  • Wounds and blood-deprived tissue
  • Compromised skin grafts
  • Air and gas embolisms (“bubbles”)
  • Clostridial myositis
  • Accelerate collagen deposition
  • Treatment of bone infection, gas gangrene
  • Post-operative colon torsions
  • Laminitis
  • Gastric ulcers, colitis and intestinal diseases
  • Lung and abdominal abscesses
  • Perinatal asphyxia (‘dummy foal’ syndrome)
  • Skin, muscle, tendinous and ligamentous injuries
  • Inflammatory diseases
  • Pancreatitis
  • Rattlesnake envenomation
  • Spider bite
  • Post cardiopulmonary arrest management
  • Near drowning, near hanging, electrocution